Conservation of HIV-1 T cell epitopes across time and clades: Validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccine

HIV genomic sequence variability has complicated efforts to generate an effective globally relevant vaccine. Regions of the viral genome conserved in sequence and across time may represent the “Achilles’ heel” of HIV. In this study, highly conserved T-cell epitopes were selected using immunoinformat...

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主要な著者: Levitz, Lauren, Koita, Ousmane A., Sangare, Kotou, Ardito, Matthew T., Boyle, Christine M., Rozehnal, John, Tounkara, Karamoko, Dao, Sounkalo M., Koné, Youssouf, Koty, Zoumana, Buus, Soren, Moise, Leonard, Martin, William D., De Groot, Anne S.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522424/
https://ncbi.nlm.nih.gov/pubmed/23102976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.10.042
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