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Heterologous expression and nonsense suppression provide insights into agonist behavior at α6β2 nicotinic acetylcholine receptors

The α6-containing subtypes of the nicotinic acetylcholine receptor (nAChR) are localized to presynaptic terminals of the dopaminergic pathways of the central nervous system. Selective ligands for these nAChRs are potentially useful in both Parkinson's disease and addiction. For these and other...

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Détails bibliographiques
Publié dans:Neuropharmacology
Auteurs principaux: Post, Michael R., Limapichat, Walrati, Lester, Henry A., Dougherty, Dennis A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635625/
https://ncbi.nlm.nih.gov/pubmed/25908401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.04.009
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