Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality

The transcription factor NF-κB has been associated with a range of pathological conditions of the heart, mainly based on its function as a master regulator of inflammation and pro-survival factor. Here, we addressed the question what effects activation of NF-κB can have during murine heart developme...

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Publicat a:PLoS One
Autors principals: Kraut, Bärbel, Maier, Harald J., Kókai, Enikö, Fiedler, Katja, Boettger, Thomas, Illing, Annett, Kostin, Sawa, Walther, Paul, Braun, Thomas, Wirth, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634958/
https://ncbi.nlm.nih.gov/pubmed/26539991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141591
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