A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

We performed a pilot proteogenomic study to compare lung adenocarcinoma to lung squamous cell carcinoma using quantitative proteomics (6-plex TMT) combined with a customized Affymetrix GeneChip. Using MaxQuant software, we identified 51,001 unique peptides that mapped to 7,241 unique proteins and fr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stewart, Paul A., Parapatics, Katja, Welsh, Eric A., Müller, André C., Cao, Haoyun, Fang, Bin, Koomen, John M., Eschrich, Steven A., Bennett, Keiryn L., Haura, Eric B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634858/
https://ncbi.nlm.nih.gov/pubmed/26539827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142162
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