Proteogenomic landscape of squamous cell lung cancer

How genomic and transcriptomic alterations affect the functional proteome in lung cancer is not fully understood. Here, we integrate DNA copy number, somatic mutations, RNA-sequencing, and expression proteomics in a cohort of 108 squamous cell lung cancer (SCC) patients. We identify three proteomic...

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I publikationen:Nat Commun
Huvudupphovsmän: Stewart, Paul A., Welsh, Eric A., Slebos, Robbert J. C., Fang, Bin, Izumi, Victoria, Chambers, Matthew, Zhang, Guolin, Cen, Ling, Pettersson, Fredrik, Zhang, Yonghong, Chen, Zhihua, Cheng, Chia-Ho, Thapa, Ram, Thompson, Zachary, Fellows, Katherine M., Francis, Jewel M., Saller, James J., Mesa, Tania, Zhang, Chaomei, Yoder, Sean, DeNicola, Gina M., Beg, Amer A., Boyle, Theresa A., Teer, Jamie K., Ann Chen, Yian, Koomen, John M., Eschrich, Steven A., Haura, Eric B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687710/
https://ncbi.nlm.nih.gov/pubmed/31395880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11452-x
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