Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

Levels of certain circulating short-chain dicarboxylacylcarnitine (SCDA), long-chain dicarboxylacylcarnitine (LCDA) and medium chain acylcarnitine (MCA) metabolites are heritable and predict cardiovascular disease (CVD) events. Little is known about the biological pathways that influence levels of m...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Kraus, William E., Muoio, Deborah M., Stevens, Robert, Craig, Damian, Bain, James R., Grass, Elizabeth, Haynes, Carol, Kwee, Lydia, Qin, Xuejun, Slentz, Dorothy H., Krupp, Deidre, Muehlbauer, Michael, Hauser, Elizabeth R., Gregory, Simon G., Newgard, Christopher B., Shah, Svati H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634848/
https://ncbi.nlm.nih.gov/pubmed/26540294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005553
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