Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

Levels of certain circulating short-chain dicarboxylacylcarnitine (SCDA), long-chain dicarboxylacylcarnitine (LCDA) and medium chain acylcarnitine (MCA) metabolites are heritable and predict cardiovascular disease (CVD) events. Little is known about the biological pathways that influence levels of m...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Kraus, William E., Muoio, Deborah M., Stevens, Robert, Craig, Damian, Bain, James R., Grass, Elizabeth, Haynes, Carol, Kwee, Lydia, Qin, Xuejun, Slentz, Dorothy H., Krupp, Deidre, Muehlbauer, Michael, Hauser, Elizabeth R., Gregory, Simon G., Newgard, Christopher B., Shah, Svati H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634848/
https://ncbi.nlm.nih.gov/pubmed/26540294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005553
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