miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo

Alzheimer's disease (AD) and related tauopathies comprise a large group of neurodegenerative diseases associated with the pathological aggregation of tau protein. While much effort has focused on understanding the function of tau, little is known about the endogenous mechanisms regulating tau m...

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發表在:Hum Mol Genet
Main Authors: Smith, Pascal Y., Hernandez-Rapp, Julia, Jolivette, Francis, Lecours, Cynthia, Bisht, Kanchan, Goupil, Claudia, Dorval, Veronique, Parsi, Sepideh, Morin, Françoise, Planel, Emmanuel, Bennett, David A., Fernandez-Gomez, Francisco-Jose, Sergeant, Nicolas, Buée, Luc, Tremblay, Marie-Ève, Calon, Frédéric, Hébert, Sébastien S.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634376/
https://ncbi.nlm.nih.gov/pubmed/26362250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv377
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