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Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease

Alzheimer's disease (AD) is a multifactorial, fatal neurodegenerative disorder characterized by the abnormal accumulation of Aβ and Tau deposits in the brain. There is no cure for AD, and failure at different clinical trials emphasizes the need for new treatments. In recent years, significant p...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Parsi, Sepideh, Smith, Pascal Y, Goupil, Claudia, Dorval, Véronique, Hébert, Sébastien S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881761/
https://ncbi.nlm.nih.gov/pubmed/26440600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.33
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