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miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo
Alzheimer's disease (AD) and related tauopathies comprise a large group of neurodegenerative diseases associated with the pathological aggregation of tau protein. While much effort has focused on understanding the function of tau, little is known about the endogenous mechanisms regulating tau m...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Hum Mol Genet |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Oxford University Press
2015
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4634376/ https://ncbi.nlm.nih.gov/pubmed/26362250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv377 |
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