miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo

Alzheimer's disease (AD) and related tauopathies comprise a large group of neurodegenerative diseases associated with the pathological aggregation of tau protein. While much effort has focused on understanding the function of tau, little is known about the endogenous mechanisms regulating tau m...

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Detaylı Bibliyografya
Yayımlandı:Hum Mol Genet
Asıl Yazarlar: Smith, Pascal Y., Hernandez-Rapp, Julia, Jolivette, Francis, Lecours, Cynthia, Bisht, Kanchan, Goupil, Claudia, Dorval, Veronique, Parsi, Sepideh, Morin, Françoise, Planel, Emmanuel, Bennett, David A., Fernandez-Gomez, Francisco-Jose, Sergeant, Nicolas, Buée, Luc, Tremblay, Marie-Ève, Calon, Frédéric, Hébert, Sébastien S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634376/
https://ncbi.nlm.nih.gov/pubmed/26362250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv377
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