miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo

Alzheimer's disease (AD) and related tauopathies comprise a large group of neurodegenerative diseases associated with the pathological aggregation of tau protein. While much effort has focused on understanding the function of tau, little is known about the endogenous mechanisms regulating tau m...

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Bibliografiska uppgifter
I publikationen:Hum Mol Genet
Huvudupphovsmän: Smith, Pascal Y., Hernandez-Rapp, Julia, Jolivette, Francis, Lecours, Cynthia, Bisht, Kanchan, Goupil, Claudia, Dorval, Veronique, Parsi, Sepideh, Morin, Françoise, Planel, Emmanuel, Bennett, David A., Fernandez-Gomez, Francisco-Jose, Sergeant, Nicolas, Buée, Luc, Tremblay, Marie-Ève, Calon, Frédéric, Hébert, Sébastien S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634376/
https://ncbi.nlm.nih.gov/pubmed/26362250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv377
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