miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo

Alzheimer's disease (AD) and related tauopathies comprise a large group of neurodegenerative diseases associated with the pathological aggregation of tau protein. While much effort has focused on understanding the function of tau, little is known about the endogenous mechanisms regulating tau m...

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Bibliografiset tiedot
Julkaisussa:Hum Mol Genet
Päätekijät: Smith, Pascal Y., Hernandez-Rapp, Julia, Jolivette, Francis, Lecours, Cynthia, Bisht, Kanchan, Goupil, Claudia, Dorval, Veronique, Parsi, Sepideh, Morin, Françoise, Planel, Emmanuel, Bennett, David A., Fernandez-Gomez, Francisco-Jose, Sergeant, Nicolas, Buée, Luc, Tremblay, Marie-Ève, Calon, Frédéric, Hébert, Sébastien S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634376/
https://ncbi.nlm.nih.gov/pubmed/26362250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv377
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