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Notch signal strength controls cell fate in the haemogenic endothelium
Acquisition of the arterial and haemogenic endothelium fates concurrently occur in the aorta–gonad–mesonephros (AGM) region prior to haematopoietic stem cell (HSC) generation. The arterial programme depends on Dll4 and the haemogenic endothelium/HSC on Jag1-mediated Notch1 signalling. How Notch1 dis...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Pub. Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4634136/ https://ncbi.nlm.nih.gov/pubmed/26465397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9510 |
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