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3-bromopyruvate enhanced daunorubicin-induced cytotoxicity involved in monocarboxylate transporter 1 in breast cancer cells

Increasing evidence demonstrates that the hexokinase inhibitor 3-bromopyruvate (3-BrPA) induces the cell apoptotic death by inhibiting ATP generation in human cancer cells. Interestingly, some tumor cell lines are less sensitive to 3-BrPA-induced apoptosis than others. Moreover, the molecular mechan...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Liu, Zhe, Sun, Yiming, Hong, Haiyu, Zhao, Surong, Zou, Xue, Ma, Renqiang, Jiang, Chenchen, Wang, Zhiwei, Li, Huabin, Liu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633897/
https://ncbi.nlm.nih.gov/pubmed/26609475
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