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No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in rats

Fluvastatin, an amphiphilic anion, shows a nonlinear increase in effective intestinal permeability (P(eff)) with increasing lumenal concentrations in rats. The main objective of this study was to investigate whether or not this observation could be attributed to an efflux-mediated transport by the m...

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Detalhes bibliográficos
Main Authors: Lindahl, Anders, Frid, Sofia, Ungell, Anna-Lena, Lennernäs, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761137/
https://ncbi.nlm.nih.gov/pubmed/11741242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps020327
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