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Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer
3-Bromopyruvate (3BP) is an energy-depleting drug that inhibits Hexokinase II activity by alkylation during glycolysis, thereby suppressing the production of ATP and inducing cell death. As such, 3BP can potentially serve as an anti-tumorigenic agent. Our previous research showed that 3BP can induce...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Bioenerg Biomembr |
|---|---|
| Prif Awduron: | , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Springer US
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546694/ https://ncbi.nlm.nih.gov/pubmed/26054380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-015-9612-1 |
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