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Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-Bromopyruvate

It has long been observed that cancer cells rely more on glycolysis to generate ATP and actively use certain glycolytic metabolic intermediates for biosynthesis. Hexokinase II (HKII) is a key glycolytic enzyme that plays a role in the regulation of the mitochondria-initiated apoptotic cell death. As...

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Detalhes bibliográficos
Main Authors: Chen, Zhao, Zhang, Hui, Lu, Weiqin, Huang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731236/
https://ncbi.nlm.nih.gov/pubmed/19285479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2009.03.003
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