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Efficacy and mechanism of action of the tyrosine kinase inhibitors gefitinib, lapatinib and neratinib in the treatment of HER2-positive breast cancer: preclinical and clinical evidence

An increasing number of tumors, including breast cancer, overexpress proteins of the epidermal growth factor receptor (EGFR) family. The interaction between family members activates signaling pathways that promote tumor progression and resistance to treatment. Human epidermal growth factor receptor...

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Detaylı Bibliyografya
Yayımlandı:Am J Cancer Res
Asıl Yazarlar: Segovia-Mendoza, Mariana, González-González, María E, Barrera, David, Díaz, Lorenza, García-Becerra, Rocío
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: e-Century Publishing Corporation 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633889/
https://ncbi.nlm.nih.gov/pubmed/26609467
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