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The addition of calcitriol or its synthetic analog EB1089 to lapatinib and neratinib treatment inhibits cell growth and promotes apoptosis in breast cancer cells

In breast cancer the use of small molecule inhibitors of tyrosine kinase activity of the ERBB family members improves survival thus represents a valuable therapeutic strategy. The addition of calcitriol, the most active metabolite of vitamin D, or some of its analogs, to conventional anticancer drug...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Segovia-Mendoza, Mariana, Díaz, Lorenza, Prado-Garcia, Heriberto, Reginato, Mauricio J, Larrea, Fernando, García-Becerra, Rocío
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523030/
https://ncbi.nlm.nih.gov/pubmed/28744399
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