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The addition of calcitriol or its synthetic analog EB1089 to lapatinib and neratinib treatment inhibits cell growth and promotes apoptosis in breast cancer cells

In breast cancer the use of small molecule inhibitors of tyrosine kinase activity of the ERBB family members improves survival thus represents a valuable therapeutic strategy. The addition of calcitriol, the most active metabolite of vitamin D, or some of its analogs, to conventional anticancer drug...

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Détails bibliographiques
Publié dans:Am J Cancer Res
Auteurs principaux: Segovia-Mendoza, Mariana, Díaz, Lorenza, Prado-Garcia, Heriberto, Reginato, Mauricio J, Larrea, Fernando, García-Becerra, Rocío
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523030/
https://ncbi.nlm.nih.gov/pubmed/28744399
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