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Inhibition of p-IκBα Ubiquitylation by Autophagy-Related Gene 7 to Regulate Inflammatory Responses to Bacterial Infection

Background. Klebsiella pneumoniae causes serious infections and healthcare burdens in humans. We have previously reported that the deficiency of autophagy-related gene (Atg) 7 in macrophages (murine alveolar macrophage cell line [MH-S]) induced irregular host immunity against K. pneumoniae and worse...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Ye, Yan, Tan, Shirui, Zhou, Xikun, Li, Xuefeng, Jundt, Michael C., Lichter, Natalie, Hidebrand, Alec, Dhasarathy, Archana, Wu, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633763/
https://ncbi.nlm.nih.gov/pubmed/26022442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv301
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