Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis

Extracellular bacteria, such as Pseudomonas aeruginosa and Klebsiella pneumoniae, have been reported to induce autophagy; however, the role and machinery of infection-induced autophagy remain elusive. We show that the pleiotropic Src kinase Lyn mediates phagocytosis and autophagosome maturation in a...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Li, Xuefeng, He, Sisi, Zhou, Xikun, Ye, Yan, Tan, Shirui, Zhang, Shuang, Li, Rongpeng, Yu, Min, Jundt, Michael C., Hidebrand, Alec, Wang, Yongsheng, Li, Guoping, Huang, Canhua, Wu, Min
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703367/
https://ncbi.nlm.nih.gov/pubmed/26735693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005363
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