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MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a

Nonalcoholic fibrosing steatohepatitis is a uniform process throughout nonalcoholic fatty liver disease (NAFLD). MicroRNAs (miRNAs) have been suggested to modulate cellular processes in liver diseases. However, the functional role of miRNAs in nonalcoholic fibrosing steatohepatitis is largely unclea...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Du, Jinghua, Niu, Xuemin, Wang, Yang, Kong, Lingbo, Wang, Rongqi, Zhang, Yuguo, Zhao, Suxian, Nan, Yuemin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633641/
https://ncbi.nlm.nih.gov/pubmed/26537990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16163
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