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MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2

Nonalcoholic fibrosing steatohepatitis is a uniform process that occurs throughout nonalcoholic fatty liver disease (NAFLD). MicroRNAs (miRNAs) have been shown to be involved in the biological processes, but the role and molecular mechanism of miRNAs in NAFLD are not entirely clear. In this study, w...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Yang, Du, Jinghua, Niu, Xuemin, Fu, Na, Wang, Rongqi, Zhang, Yuguo, Zhao, Suxian, Sun, Dianxing, Nan, Yuemin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520685/
https://ncbi.nlm.nih.gov/pubmed/28518142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.10
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