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MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a

Nonalcoholic fibrosing steatohepatitis is a uniform process throughout nonalcoholic fatty liver disease (NAFLD). MicroRNAs (miRNAs) have been suggested to modulate cellular processes in liver diseases. However, the functional role of miRNAs in nonalcoholic fibrosing steatohepatitis is largely unclea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Du, Jinghua, Niu, Xuemin, Wang, Yang, Kong, Lingbo, Wang, Rongqi, Zhang, Yuguo, Zhao, Suxian, Nan, Yuemin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633641/
https://ncbi.nlm.nih.gov/pubmed/26537990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16163
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