Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P(2)

Phagocytosis is a highly conserved process whereby phagocytic cells engulf pathogens and apoptotic bodies. The present study focused on the role of inositol polyphosphate-4-phosphatase type I (Inpp4a) in phagocytosis. Raw264.7 cells that express shRNA against Inpp4a (shInpp4a cells) showed significa...

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Veröffentlicht in:PLoS One
Hauptverfasser: Nigorikawa, Kiyomi, Hazeki, Kaoru, Sasaki, Junko, Omori, Yumio, Miyake, Mikiko, Morioka, Shin, Guo, Ying, Sasaki, Takehiko, Hazeki, Osamu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633150/
https://ncbi.nlm.nih.gov/pubmed/26535897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142091
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