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Direct Measurements of Local Coupling between Myosin Molecules Are Consistent with a Model of Muscle Activation

Muscle contracts due to ATP-dependent interactions of myosin motors with thin filaments composed of the proteins actin, troponin, and tropomyosin. Contraction is initiated when calcium binds to troponin, which changes conformation and displaces tropomyosin, a filamentous protein that wraps around th...

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Pubblicato in:PLoS Comput Biol
Autori principali: Walcott, Sam, Kad, Neil M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633106/
https://ncbi.nlm.nih.gov/pubmed/26536123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004599
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