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The function, regulation and therapeutic implications of the tumor suppressor protein, PML
The tumor suppressor protein, promyelocytic leukemia protein (PML), was originally identified in acute promyelocytic leukemia due to a chromosomal translocation between chromosomes 15 and 17. PML is the core component of subnuclear structures called PML nuclear bodies (PML-NBs), which are disrupted...
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| Опубликовано в: : | Cell Biosci |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632682/ https://ncbi.nlm.nih.gov/pubmed/26539288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0051-9 |
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