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Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity

Oxidative stress is a consequence of an imbalance between reactive oxygen species (ROS) production and the ability of the cytoprotective system to detoxify the reactive intermediates. The tumor suppressor promyelocytic leukemia protein (PML) functions as a stress sensor. Loss of PML results in impai...

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Détails bibliographiques
Auteurs principaux: Guo, Shuang, Cheng, Xiwen, Lim, Jun-Hee, Liu, Yu, Kao, Hung-Ying
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142619/
https://ncbi.nlm.nih.gov/pubmed/24943846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-11-0692
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