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The function, regulation and therapeutic implications of the tumor suppressor protein, PML

The tumor suppressor protein, promyelocytic leukemia protein (PML), was originally identified in acute promyelocytic leukemia due to a chromosomal translocation between chromosomes 15 and 17. PML is the core component of subnuclear structures called PML nuclear bodies (PML-NBs), which are disrupted...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Guan, Dongyin, Kao, Hung-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632682/
https://ncbi.nlm.nih.gov/pubmed/26539288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0051-9
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