ARGININOSUCCINATE SYNTHASE CONDITIONS THE RESPONSE TO ACUTE AND CHRONIC ETHANOL-INDUCED LIVER INJURY IN MICE

BACKGROUND AND AIM: Argininosuccinate synthase (ASS) is the rate-limiting enzyme in both the urea and the l-citrulline/nitric oxide (NO·) cycles regulating protein catabolism, ammonia levels and NO· generation (1-2). Since a proteomics analysis identified ASS and nitric oxide synthase-2 (NOS2) as co...

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Vydáno v:Hepatology
Hlavní autoři: Leung, Tung Ming, Lu, Yongke, Yan, Wei, Morón-Concepción, Jose A., Ward, Stephen C., Ge, Xiaodong, de la Rosa, Laura Conde, Nieto, Natalia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632528/
https://ncbi.nlm.nih.gov/pubmed/22213272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25543
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