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LMO2 at 25 years: a paradigm of chromosomal translocation proteins

LMO2 was first discovered through proximity to frequently occurring chromosomal translocations in T cell acute lymphoblastic leukaemia (T-ALL). Subsequent studies on its role in tumours and in normal settings have highlighted LMO2 as an archetypical chromosomal translocation oncogene, activated by a...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Chambers, Jennifer, Rabbitts, Terence H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632508/
https://ncbi.nlm.nih.gov/pubmed/26108219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150062
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