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The RCAN1 inhibits NF-κB and suppresses lymphoma growth in mice
Nuclear factor-κB (NF-κB) has a vital role in cell survival. Inhibition of NF-κB has been proven to be an efficient therapeutic pathway for various cancers. Activation of NF-κB is mainly through serine residues' phosphorylation of inhibitor of κBα (IκBα) by IKK complex. Phosphorylation at tyros...
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| Veröffentlicht in: | Cell Death Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632290/ https://ncbi.nlm.nih.gov/pubmed/26492364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.260 |
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