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SEC14L2 enables pan-genotype HCV replication in cell culture

Since its discovery in 1989, efforts to grow clinical isolates of the hepatitis C virus (HCV) in cell culture have met with limited success. Only the JFH-1 isolate has the capacity to replicate efficiently in cultured hepatoma cells without cell culture-adaptive mutations(1-3). We hypothesized that...

詳細記述

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書誌詳細
出版年:Nature
主要な著者: Saeed, Mohsan, Andreo, Ursula, Chung, Hyo-Young, Espiritu, Christine, Branch, Andrea D., Silva, Jose M., Rice, Charles M.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632207/
https://ncbi.nlm.nih.gov/pubmed/26266980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14899
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