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SEC14L2 enables pan-genotype HCV replication in cell culture
Since its discovery in 1989, efforts to grow clinical isolates of the hepatitis C virus (HCV) in cell culture have met with limited success. Only the JFH-1 isolate has the capacity to replicate efficiently in cultured hepatoma cells without cell culture-adaptive mutations(1-3). We hypothesized that...
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| Izdano u: | Nature |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632207/ https://ncbi.nlm.nih.gov/pubmed/26266980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14899 |
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