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SEC14L2 enables pan-genotype HCV replication in cell culture
Since its discovery in 1989, efforts to grow clinical isolates of the hepatitis C virus (HCV) in cell culture have met with limited success. Only the JFH-1 isolate has the capacity to replicate efficiently in cultured hepatoma cells without cell culture-adaptive mutations(1-3). We hypothesized that...
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出版年: | Nature |
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主要な著者: | , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632207/ https://ncbi.nlm.nih.gov/pubmed/26266980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14899 |
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