Pan-Genotype Hepatitis E Virus Replication in Stem Cell-derived Hepatocellular Systems

BACKGROUND & AIMS: The 4 genotypes of hepatitis E virus (HEV) that infect humans (genotypes 1–4) vary in geographical distribution, transmission, and pathogenesis. Little is known about the properties of HEV or its hosts that contribute to these variations. Primary isolates grow poorly in cell c...

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Gepubliceerd in:Gastroenterology
Hoofdauteurs: Wu, Xianfang, Thi, Viet Loan Dao, Liu, Peng, Takacs, Constantin N., Xiang, Kuanhui, Andrus, Linda, Gouttenoire, Jérôme, Moradpour, Darius, Rice, Charles M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811326/
https://ncbi.nlm.nih.gov/pubmed/29277559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.10.041
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