Palmitoylation mediates membrane association of hepatitis E virus ORF3 protein and is required for infectious particle secretion

Hepatitis E virus (HEV) is a positive-strand RNA virus encoding 3 open reading frames (ORF). HEV ORF3 protein is a small, hitherto poorly characterized protein involved in viral particle secretion and possibly other functions. Here, we show that HEV ORF3 protein forms membrane-associated oligomers....

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Pubblicato in:PLoS Pathog
Autori principali: Gouttenoire, Jérôme, Pollán, Angela, Abrami, Laurence, Oechslin, Noémie, Mauron, Johann, Matter, Maxime, Oppliger, Joël, Szkolnicka, Dagmara, Dao Thi, Viet Loan, van der Goot, F. Gisou, Moradpour, Darius
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307819/
https://ncbi.nlm.nih.gov/pubmed/30532200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007471
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