Efficient Replication of Genotype 3a and 4a Hepatitis C Virus Replicons in Human Hepatoma Cells

Despite recent advances in the treatment of hepatitis C, the quest for pan-genotype, effective, and well-tolerated inhibitors continues. To facilitate these efforts, it is desirable to have in vitro replication systems for all major HCV genotypes. However, cell culture replication systems exist for...

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Autors principals: Saeed, Mohsan, Scheel, Troels K. H., Gottwein, Judith M., Marukian, Svetlana, Dustin, Lynn B., Bukh, Jens, Rice, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457365/
https://ncbi.nlm.nih.gov/pubmed/22869572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01256-12
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