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SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression

Colorectal cancer (CRC) is the third most common cancer in the world, and second leading cause of cancer deaths in the US. Although, anti-EGFR therapy is commonly prescribed for CRC, patients harboring mutations in KRAS or BRAF show poor treatment response, indicating an ardent demand for new therap...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Tiwari, R, Pandey, S K, Goel, S, Bhatia, V, Shukla, S, Jing, X, Dhanasekaran, S M, Ateeq, B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632074/
https://ncbi.nlm.nih.gov/pubmed/26258891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.23
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