SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression

Colorectal cancer (CRC) is the third most common cancer in the world, and second leading cause of cancer deaths in the US. Although, anti-EGFR therapy is commonly prescribed for CRC, patients harboring mutations in KRAS or BRAF show poor treatment response, indicating an ardent demand for new therap...

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Publicat a:Oncogenesis
Autors principals: Tiwari, R, Pandey, S K, Goel, S, Bhatia, V, Shukla, S, Jing, X, Dhanasekaran, S M, Ateeq, B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632074/
https://ncbi.nlm.nih.gov/pubmed/26258891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.23
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