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SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression

Colorectal cancer (CRC) is the third most common cancer in the world, and second leading cause of cancer deaths in the US. Although, anti-EGFR therapy is commonly prescribed for CRC, patients harboring mutations in KRAS or BRAF show poor treatment response, indicating an ardent demand for new therap...

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Bibliografiska uppgifter
I publikationen:Oncogenesis
Huvudupphovsmän: Tiwari, R, Pandey, S K, Goel, S, Bhatia, V, Shukla, S, Jing, X, Dhanasekaran, S M, Ateeq, B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632074/
https://ncbi.nlm.nih.gov/pubmed/26258891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.23
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