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Exact Inference for Hardy-Weinberg Proportions with Missing Genotypes: Single and Multiple Imputation
This paper addresses the issue of exact-test based statistical inference for Hardy−Weinberg equilibrium in the presence of missing genotype data. Missing genotypes often are discarded when markers are tested for Hardy−Weinberg equilibrium, which can lead to bias in the statistical inference about eq...
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| Publicado en: | G3 (Bethesda) |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Genetics Society of America
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632056/ https://ncbi.nlm.nih.gov/pubmed/26377959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.022111 |
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