CUG-BP1 regulates RyR1 ASI alternative splicing in skeletal muscle atrophy

RNA binding protein is identified as an important mediator of aberrant alternative splicing in muscle atrophy. The altered splicing of calcium channels, such as ryanodine receptors (RyRs), plays an important role in impaired excitation-contraction (E-C) coupling in muscle atrophy; however, the regul...

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Udgivet i:Sci Rep
Main Authors: Tang, Yinglong, Wang, Huiwen, Wei, Bin, Guo, Yuting, Gu, Lei, Yang, Zhiguang, Zhang, Qing, Wu, Yanyun, Yuan, Qi, Zhao, Gang, Ji, Guangju
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632035/
https://ncbi.nlm.nih.gov/pubmed/26531141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16083
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