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CUG-BP1 regulates RyR1 ASI alternative splicing in skeletal muscle atrophy

RNA binding protein is identified as an important mediator of aberrant alternative splicing in muscle atrophy. The altered splicing of calcium channels, such as ryanodine receptors (RyRs), plays an important role in impaired excitation-contraction (E-C) coupling in muscle atrophy; however, the regul...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tang, Yinglong, Wang, Huiwen, Wei, Bin, Guo, Yuting, Gu, Lei, Yang, Zhiguang, Zhang, Qing, Wu, Yanyun, Yuan, Qi, Zhao, Gang, Ji, Guangju
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632035/
https://ncbi.nlm.nih.gov/pubmed/26531141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16083
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