The Consequences of Replicating in the Wrong Orientation: Bacterial Chromosome Duplication without an Active Replication Origin

Chromosome replication is regulated in all organisms at the assembly stage of the replication machinery at specific origins. In Escherichia coli, the DnaA initiator protein regulates the assembly of replication forks at oriC. This regulation can be undermined by defects in nucleic acid metabolism. I...

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Bibliografski detalji
Izdano u:mBio
Glavni autori: Dimude, Juachi U., Stockum, Anna, Midgley-Smith, Sarah L., Upton, Amy L., Foster, Helen A., Khan, Arshad, Saunders, Nigel J., Retkute, Renata, Rudolph, Christian J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631800/
https://ncbi.nlm.nih.gov/pubmed/26530381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01294-15
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