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Avoiding chromosome pathology when replication forks collide

Chromosome duplication normally initiates via the assembly of replication fork complexes at defined origins(1,2). DNA synthesis by any one fork is thought to cease when it meets another travelling in the opposite direction, at which stage the replication machinery may simply dissociate before the na...

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Detalhes bibliográficos
Main Authors: Rudolph, Christian J., Upton, Amy L., Stockum, Anna, Nieduszynski, Conrad A., Lloyd, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819906/
https://ncbi.nlm.nih.gov/pubmed/23892781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12312
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