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Avoiding chromosome pathology when replication forks collide

Chromosome duplication normally initiates via the assembly of replication fork complexes at defined origins(1,2). DNA synthesis by any one fork is thought to cease when it meets another travelling in the opposite direction, at which stage the replication machinery may simply dissociate before the na...

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Autors principals: Rudolph, Christian J., Upton, Amy L., Stockum, Anna, Nieduszynski, Conrad A., Lloyd, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819906/
https://ncbi.nlm.nih.gov/pubmed/23892781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12312
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