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Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models
A low level of tissue oxygen (hypoxia) is a physiological feature of a wide range of diseases, from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive hydroxylase enzymes, which regulate the protein stability of hypoxia-inducible factor α (HIF-α) transcription factors. When stabilis...
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| Publié dans: | Dis Model Mech |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631790/ https://ncbi.nlm.nih.gov/pubmed/26512123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.021865 |
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