Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb), becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and deve...

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Главные авторы: Elks, Philip M., Brizee, Sabrina, van der Vaart, Michiel, Walmsley, Sarah R., van Eeden, Fredericus J., Renshaw, Stephen A., Meijer, Annemarie H.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868520/
https://ncbi.nlm.nih.gov/pubmed/24367256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003789
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