Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

Tuberculosis is a current major world-health problem, exacerbated by the causative pathogen, Mycobacterium tuberculosis (Mtb), becoming increasingly resistant to conventional antibiotic treatment. Mtb is able to counteract the bactericidal mechanisms of leukocytes to survive intracellularly and deve...

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Detalhes bibliográficos
Main Authors: Elks, Philip M., Brizee, Sabrina, van der Vaart, Michiel, Walmsley, Sarah R., van Eeden, Fredericus J., Renshaw, Stephen A., Meijer, Annemarie H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868520/
https://ncbi.nlm.nih.gov/pubmed/24367256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003789
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